Zenrelia, an effective, convenient, and safe once-daily oral JAK inhibitor, continues its launch progress globally, gaining approval from the United Kingdom’s Veterinary Medicines Directorate in August 2025. Additionally, launch progress continues across the EU and Great Britain with product supply now in market for veterinarians and pet owners.
“Now we have a medication that is once a day right from the start. I think it will really help improve that owner, patient, pet bond, it will hopefully help reduce caregiver burden and will improve patient and carer quality of life as well,” said Dr. Victoria Robinson BVM&S, BSc, CertAVP (VD), DipECVD, MRCVS, RCVS and European Specialist in Veterinary Dermatology. “Knowing what I currently know about Zenrelia, I am keen to use it in the clinic and start prescribing it.”
This launch represents a pivotal milestone within the international canine dermatology market, offering a single daily dose for controlling pruritus (itching) associated with allergic dermatitis and atopic dermatitis in dogs over 12 months of age. Zenrelia is now available in the European Union, Great Britain, Brazil, Canada, Japan, and the United States. The Zenrelia EU label is consistent with other markets outside North America where the product has already been approved.
“Zenrelia joins our exciting, growing international pet health portfolio, including AdTab, Credelio Plus, Galliprant (grapiprant tablets) and others,” said Ramiro Cabral, Executive Vice President, Elanco International. “We are very pleased with the results we are seeing in the global market, with more than half a million dogs treated with Zenrelia.”
As part of the EU approval process, Elanco conducted a head-to-head non-inferiority study versus the marketplace incumbent, Apoquel. The randomized, double-blind study of 338 client-owned dogs with confirmed atopic dermatitis was conducted across 25 study sites in four countries. The study is published in a leading peer-reviewed, international journal, Veterinary Dermatology: https://doi.org/10.1111/vde.13319.
